Primary breast T cell lymphoma – a rare case report

Primary breast lymphomas (PBL) are an exceptionally rare form of extranodal non-Hodgkin lymphoma (NHL), occurring in less than 0.5% all malignancies.1 T-cell (TCL) is even rarer entity, accounting for only 6% lymphomas. It has aggressive but poorly understood clinical course, and non-specific features that can mimic inflammatory carcinoma (oedema, skin changes mastalgia).1 Currently, there no standard treatment protocol PBL, a multimodal approach using diagnostic lumpectomy combined with chemotherapy and/or radiation therapy recommended, versus radical mastectomy alone overall survival benefit higher all-cause mortality rates.2 We present case 64 year old female 12 month history right pain changes. Clinical radiological examination (mammogram ultrasound) revealed focal lesion or lymphadenopathy. Multiple biopsies showed evidence malignancy. The patient was also treated IV antibiotics improvement. Due to persistent symptoms concern carcinoma, performed. Haematoxylin eosin (H&E) stained sections molecular testing (immunohistochemistry T cell gene rearrangement) confirmed primary lymphoma. References 1. Shim E, Song SE, Seo BK, Kim YS, Son GS. Lymphoma affecting the breast: pictorial review imaging findings. J Breast Cancer 2013; 16: 254–265. 2. Jennings WC, Baker RS, Murray SS, et al. lymphoma: role importance lymph node status. Ann Surg 2007; 245: 784–789.